Jitteriness and seizures both can be signs of neonatal sepsis but usually in conjunction with respiratory distress, heart rate, and temperature instability. ![]() Neonatal abstinence syndrome typically is seen in opiate withdrawal, but it encompasses withdrawal from a wide range of both illicit (heroin, cocaine, amphetamines, phencyclidine, ethyl alcohol ) and prescription drugs (including prescription opiates, benzodiazepines, barbiturates, and selective serotonin reuptake inhibitors antidepressants). Other electrolyte testing was within normal limits. ![]() Point-of-care glucose testing on this infant remained normal, and he did not have any of the other obvious associated risk factors for hypoglycemia (such as being large for gestational age or small for gestational age ). The most common electrolyte abnormality seen in infants with jitteriness is hypoglycemia. The differential diagnosis for a newborn with jitteriness is shown in Table 1. His mother also stated he was not latching well on the breast and had ingested only 10 mL of supplemental formula. Six hours later on routine rounds, the infant‘s examination revealed significant hypertonia, irritability, and jitteriness (high-frequency rhythmic tremors involving all extremities that were able to be stopped with firm but gentle pressure of the extremity). The infant’s initial point-of-care glucose testing was normal (at 83 mg/dL) and he was left with the mother for skin-to-skin time and breastfeeding. The infant’s weight was 3240 g, gestational age examination was consistent with full term status, and he plotted appropriately for all other growth parameters on the growth chart (weight, 45% head circumference, 50% length, 50%). Gonorrhea/chlamydia and group B Streptococcus (GBS) cultures were not done. Her intrapartum urine drug screening was negative.Ī full prenatal lab profile for the infant was not available at the time of delivery, but prenatal labs drawn were subsequently found to be: AB positive blood type with negative antibody screen HIV negative RPR nonreactive HBsAg negative MRSA culture negative sickle test negative and rubella immune. She also endorsed tobacco smoking (4 to 5 cigarettes per day) but denied alcohol or other prescription or illicit drug use. Upon further questioning, the mother said that she had been prescribed Percocet by her dentist, which she had used approximately twice daily for the past 3 weeks for dental pain. In the delivery room, the infant was noted to be very jittery with oscillatory tremor of both upper and lower extremities. ![]() The delivery was precipitous: Rupture of membranes was 3 hours in duration with clear fluid no intrapartum medications were administered and the infant’s Apgar scores were 9 and 9 at 1 and 5 minutes, respectively. (2007).A full-term male infant was born at 40.3 weeks gestational age via vaginal delivery to a 29-year-old single G6 P30204 mother with limited prenatal care (3 visits) and short interval pregnancy. The safety of ingested caffeine: A comprehensive review. Understanding DiGeorge syndrome (22q11.2 deletion syndrome). ALS Association applauds FDA for speedy approval of new ALS drug Radicava (edaravone). You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations.
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